Medical ArticlesClinic NewsCancer Screening

miSignal Urine-Based Cancer Screening Now Available

This is a cancer screening that detects cancer using a new mechanism. miSignal can screen for multiple cancers with a urine test. You can check for esophageal cancer, lung cancer, breast cancer, stomach cancer, colon cancer, bladder cancer, pancreatic cancer, kidney cancer, ovarian cancer, and prostate cancer. Cancer cells come out...

About this translation This English version is provided for convenience. If any wording differs from the Japanese version, the Japanese version applies.

This is a cancer screening that detects cancer using a new mechanism.

miSignal can screen for multiple cancers with a urine test.
Esophageal cancer, lung cancer, breast cancer, stomach cancer, colon cancer, bladder cancer, pancreatic cancer, kidney cancer, ovarian cancer, prostate cancer
You can check.

Substances called microRNAs produced by cancer cells also appear in the urine. This is analyzed using a next-generation sequencer, and the resulting pattern is analyzed using a machine learning model called a support vector machine. With this latest method, it is now possible to detect early-stage cancers, for which previously used tumor markers were weak, with high sensitivity and specificity (the ability to judge the presence of a disease as ``yes'' and the absence of a disease as ``absent'') (1).

We will start accepting inspections from November 1, 2025.

About specimen handling

At our clinic, clinical laboratory technician staff manages the samples, stores them in a temperature-controlled refrigerator, and ships them to the testing center. The test results will be explained to you at the outpatient clinic after 6 weeks, and if the patient is at high risk, the patient will be examined or referred to a higher-level medical institution.

If you would like to be tested, please come to our outpatient clinic or contact us by phone.

In consideration of the possibility that the test results may be missed or the patient may not be able to receive the test results if they go directly to a general hospital, we do not deliver the test results only to your home.

price

miSignal is not covered by insurance and will incur the following testing costs.

My Signal price (excluding tax)63,000 yen
MySignal sample storage shipping fee (excluding tax)5,000 yen
MySignal judgment fee (excluding tax)3,000 yen
Total (excluding tax)71,000 yen

I actually tried it

I collected the urine, put it in a container, stored the sample in a special refrigerator, and submitted it, and the analysis results were incorrect.

After 6 weeks, the report was completed in the form of a test result booklet.

We found that the risk for all cancers is low.
I was particularly concerned about stomach cancer, as it can occur even at a young age.

My microRNA cancer risk was low, and my personal cancer risk, which is my lifestyle and biological risk, was also low.

I thought that now I can work energetically starting tomorrow.

References

  1. Baba S, et al. A noninvasive urinary microRNA-based assay for the detection of pancreatic cancer from early to late stages: a case–control study. EClinicalMedicine. 2024; 0:100(https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00515-7/fulltext)